7Y9S

Cryo-EM structure of apo SARS-CoV-2 Omicron spike protein (S-2P-GSAS)

Summary for 7Y9S

Entry DOI	10.2210/pdb7y9s/pdb
EMDB information	33690
Descriptor	Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sars-cov-2, omicron, spike protein, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
Total number of polymer chains	3
Total formula weight	427962.91
Authors	Zhao, Z.N.,Xie, Y.F.,Qi, J.X.,Gao, G.F. (deposition date: 2022-06-26, release date: 2022-08-31, Last modification date: 2022-09-07)
Primary citation	Zhao, Z.,Zhou, J.,Tian, M.,Huang, M.,Liu, S.,Xie, Y.,Han, P.,Bai, C.,Han, P.,Zheng, A.,Fu, L.,Gao, Y.,Peng, Q.,Li, Y.,Chai, Y.,Zhang, Z.,Zhao, X.,Song, H.,Qi, J.,Wang, Q.,Wang, P.,Gao, G.F. Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13:4958-4958, 2022 Cited by PubMed: 36002453 DOI: 10.1038/s41467-022-32665-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation