7X9Q
Crystal structure of human STING complexed with compound BSP16
Summary for 7X9Q
Entry DOI | 10.2210/pdb7x9q/pdb |
Descriptor | Stimulator of interferon genes protein, (2R)-4-(5,6-dimethoxy-1-benzoselenophen-2-yl)-2-ethyl-4-oxidanylidene-butanoic acid (3 entities in total) |
Functional Keywords | sting agonists, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 26389.57 |
Authors | |
Primary citation | Feng, X.,Pan, L.,Qian, Z.,Liu, D.,Guan, X.,Feng, L.,Song, B.,Xu, X.,Tan, N.,Ma, Y.,Li, Z.,Wang, Z.,Bian, J. Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor Agents. J.Med.Chem., 65:15048-15065, 2022 Cited by PubMed: 36069713DOI: 10.1021/acs.jmedchem.2c00634 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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