7X4T

LpCdnE UMPNPP Mg complex

Summary for 7X4T

Entry DOI	10.2210/pdb7x4t/pdb
Related	7X4A 7X4C 7X4F 7X4G 7X4P 7X4Q
Descriptor	Cyclic dipyrimidine nucleotide synthase, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	cd-ntase, cgas, cyclic dinucleotide, complex, substrate analogue, transferase
Biological source	Legionella pneumophila
Total number of polymer chains	2
Total formula weight	72260.69
Authors	Chen, Y.,Ko, T.P.,Yang, C.S.,Wang, Y.C.,Hou, M.H. (deposition date: 2022-03-03, release date: 2023-03-08, Last modification date: 2023-11-29)
Primary citation	Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun, 14:5078-5078, 2023 Cited by PubMed: 37604815 DOI: 10.1038/s41467-023-40787-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation