7X3A
NMR solution structure of the 1:1 complex of a pyridostatin (PDS) bound to a G-quadruplex MYT1L
Summary for 7X3A
Entry DOI | 10.2210/pdb7x3a/pdb |
Descriptor | G-quadruplex DNA MYT1L, 4-(2-azanylethoxy)-N2,N6-bis[4-(2-azanylethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide (2 entities in total) |
Functional Keywords | g-quadruplex, complex, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 9813.54 |
Authors | Liu, L.-Y.,Mao, Z.-W.,Liu, W. (deposition date: 2022-02-28, release date: 2022-06-08, Last modification date: 2024-05-15) |
Primary citation | Liu, L.-Y.,Ma, T.Z.,Zeng, Y.L.,Liu, W.,Mao, Z.-W. Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes. J.Am.Chem.Soc., 144:11878-11887, 2022 Cited by PubMed: 35749293DOI: 10.1021/jacs.2c04775 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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