7WVP

Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C2 state

Summary for 7WVP

Entry DOI	10.2210/pdb7wvp/pdb
EMDB information	32856
Descriptor	Angiotensin-converting enzyme 2, Spike glycoprotein (2 entities in total)
Functional Keywords	sars-cov-2, omicron, spike protein, ace2, viral protein, hydrolase-viral protein complex
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	493040.37
Authors	Han, W.Y.,Wang, Y.F. (deposition date: 2022-02-10, release date: 2022-04-06, Last modification date: 2022-05-04)
Primary citation	Hong, Q.,Han, W.,Li, J.,Xu, S.,Wang, Y.,Xu, C.,Li, Z.,Wang, Y.,Zhang, C.,Huang, Z.,Cong, Y. Molecular basis of receptor binding and antibody neutralization of Omicron. Nature, 604:546-552, 2022 Cited by PubMed: 35228716 DOI: 10.1038/s41586-022-04581-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation