7WTH

SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv264

Summary for 7WTH

• Entry DOI: 10.2210/pdb7wth/pdb
• EMDB information: 32786
• Descriptor: Spike protein S1, Light chain of XGv264, Heavy chain of XGv264 (3 entities in total)
• Functional Keywords: sars-cov-2, omicron, spike-fab complex, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 3
• Total formula weight: 47036.06

Authors

Wang, X.,Fu, W. (deposition date: 2022-02-04, release date: 2022-12-14, Last modification date: 2025-07-02)

• Primary citation: Wang, L.,Fu, W.,Bao, L.,Jia, Z.,Zhang, Y.,Zhou, Y.,Wu, W.,Wu, J.,Zhang, Q.,Gao, Y.,Wang, K.,Wang, Q.,Qin, C.,Wang, X.; Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages.; Cell Res., 32:691-694, 2022; PubMed: 35672388; DOI: 10.1038/s41422-022-00677-z

Experimental method

ELECTRON MICROSCOPY (4.3 Å)