7WP6

Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies

Summary for 7WP6

• Entry DOI: 10.2210/pdb7wp6/pdb
• EMDB information: 32676
• Descriptor: 36H6 heavy chain, 83H7 light chain, 83H7 heavy chain, ... (9 entities in total)
• Functional Keywords: sars-cov-2, spike, vaccine, neutralizing antibody, cryo-em, viral protein, immune system-viral protein complex, immune system/viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 7
• Total formula weight: 96455.18

Authors

Zheng, Q.,Sun, H.,Yuan, Q.,Li, S.,Xia, N. (deposition date: 2022-01-23, release date: 2023-03-01, Last modification date: 2023-09-13)

• Primary citation: Wu, Y.,Wang, S.,Zhang, Y.,Yuan, L.,Zheng, Q.,Wei, M.,Shi, Y.,Wang, Z.,Ma, J.,Wang, K.,Nie, M.,Xiao, J.,Huang, Z.,Chen, P.,Guo, H.,Lan, M.,Xu, J.,Hou, W.,Hong, Y.,Chen, D.,Sun, H.,Xiong, H.,Zhou, M.,Liu, C.,Guo, W.,Guo, H.,Gao, J.,Gan, C.,Li, Z.,Zhang, H.,Wang, X.,Li, S.,Cheng, T.,Zhao, Q.,Chen, Y.,Wu, T.,Zhang, T.,Zhang, J.,Cao, H.,Zhu, H.,Yuan, Q.,Guan, Y.,Xia, N.; Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.; Cell Host Microbe, 30:1732-1744.e7, 2022; PubMed: 36323313; DOI: 10.1016/j.chom.2022.10.011

Experimental method

ELECTRON MICROSCOPY (3.81 Å)