7WP5

Cryo-EM structure of SARS-CoV-2 Omicron S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)

Summary for 7WP5

• Entry DOI: 10.2210/pdb7wp5/pdb
• EMDB information: 32669
• Descriptor: VacW-209 light chain, VacW-209 heavy chain, Spikeprotein S1, ... (4 entities in total)
• Functional Keywords: sars-cov-2, omicron variant, spike, neutralizing antibody, cryo-em, viral protein, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 48037.49

Authors

Zheng, Q.,Sun, H.,Ju, B.,Zhang, Z.,Li, S.,Xia, N. (deposition date: 2022-01-22, release date: 2022-07-13)

• Primary citation: Ju, B.,Zheng, Q.,Guo, H.,Fan, Q.,Li, T.,Song, S.,Sun, H.,Shen, S.,Zhou, X.,Xue, W.,Cui, L.,Zhou, B.,Li, S.,Xia, N.,Zhang, Z.; Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.; Cell Res., 32:491-494, 2022; PubMed: 35260792; DOI: 10.1038/s41422-022-00638-6

Experimental method

ELECTRON MICROSCOPY (3.9 Å)