7WHD

SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (2u1d)

Summary for 7WHD

Entry DOI	10.2210/pdb7whd/pdb
EMDB information	32499
Descriptor	Spike glycoprotein, antibody ZB8 heavy chain, antibody ZB8 light chain, ... (5 entities in total)
Functional Keywords	sars-cov-2 spike, receptor binding domain, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More
Total number of polymer chains	9
Total formula weight	524188.14
Authors	Zeng, J.W.,Wang, X.W.,Ge, J.W.,Wang, Z.Y. (deposition date: 2021-12-30, release date: 2023-01-18, Last modification date: 2023-09-06)
Primary citation	Zhou, B.,Zhou, R.,Chan, J.F.,Zeng, J.,Zhang, Q.,Yuan, S.,Liu, L.,Robinot, R.,Shan, S.,Liu, N.,Ge, J.,Kwong, H.Y.,Zhou, D.,Xu, H.,Chan, C.C.,Poon, V.K.,Chu, H.,Yue, M.,Kwan, K.Y.,Chan, C.Y.,Chan, C.C.,Chik, K.K.,Du, Z.,Au, K.K.,Huang, H.,Man, H.O.,Cao, J.,Li, C.,Wang, Z.,Zhou, J.,Song, Y.,Yeung, M.L.,To, K.K.,Ho, D.D.,Chakrabarti, L.A.,Wang, X.,Zhang, L.,Yuen, K.Y.,Chen, Z. SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters 1 . Emerg Microbes Infect, 12:2245921-2245921, 2023 Cited by PubMed: 37542391 DOI: 10.1080/22221751.2023.2245921 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.65 Å)

Structure validation