7VWG
Human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic alpha/delta dual agonist JKPL38
Summary for 7VWG
| Entry DOI | 10.2210/pdb7vwg/pdb |
| Descriptor | Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside, (2S)-2-[[4-propoxy-3-[[[4-(trifluoromethyl)phenyl]carbonylamino]methyl]phenyl]methyl]butanoic acid, ... (4 entities in total) |
| Functional Keywords | nuclear receptor, protein-ligand complex, ppar, transcription |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 64486.88 |
| Authors | Oyama, T.,Miyachi, H. (deposition date: 2021-11-10, release date: 2022-02-09, Last modification date: 2023-11-29) |
| Primary citation | Oyama, T.,Takiguchi, K.,Miyachi, H. Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor delta in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative. Acta Crystallogr.,Sect.F, 78:81-87, 2022 Cited by DOI: 10.1107/S2053230X22000449PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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