7VFW

Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to CaV2.2-blocker1

Summary for 7VFW

• Entry DOI: 10.2210/pdb7vfw/pdb
• EMDB information: 31961
• Descriptor: Voltage-dependent N-type calcium channel subunit alpha-1B, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: voltage gated calcium channel, n-type, complex, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 463262.13

Authors

Dong, Y.,Gao, Y.,Wang, Y.,Zhao, Y. (deposition date: 2021-09-13, release date: 2021-11-03, Last modification date: 2022-02-16)

• Primary citation: Dong, Y.,Gao, Y.,Xu, S.,Wang, Y.,Yu, Z.,Li, Y.,Li, B.,Yuan, T.,Yang, B.,Zhang, X.C.,Jiang, D.,Huang, Z.,Zhao, Y.; Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2.; Cell Rep, 37:109931-109931, 2021; PubMed: 34731621; DOI: 10.1016/j.celrep.2021.109931

Experimental method

ELECTRON MICROSCOPY (3.3 Å)