7UZ8
Structure of the SARS-CoV-2 Omicron BA.1 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Summary for 7UZ8
Entry DOI | 10.2210/pdb7uz8/pdb |
EMDB information | 26882 |
Descriptor | Spike glycoprotein, M8a-31 Fab heavy chain, M8a-31 Fab light chain, ... (5 entities in total) |
Functional Keywords | immune system, neutralizing antibody, immune system-viral protein complex, immune system/viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 9 |
Total formula weight | 571744.87 |
Authors | Fan, C.,Bjorkman, P.J. (deposition date: 2022-05-08, release date: 2022-12-07, Last modification date: 2022-12-28) |
Primary citation | Fan, C.,Cohen, A.A.,Park, M.,Hung, A.F.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Gao, H.,Kakutani, L.M.,Wu, Z.,Kleanthous, H.,Malecek, K.E.,Williams, J.C.,Bjorkman, P.J. Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes. Immunity, 55:2419-, 2022 Cited by PubMed: 36370711DOI: 10.1016/j.immuni.2022.10.019 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
Download full validation report