7UHF

Human L-type voltage-gated calcium channel Cav1.3 in the presence of cinnarizine at 3.1 Angstrom resolution

Summary for 7UHF

• Entry DOI: 10.2210/pdb7uhf/pdb
• EMDB information: 26513 26514
• Descriptor: Voltage-dependent L-type calcium channel subunit alpha-1D, CHOLESTEROL HEMISUCCINATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... (11 entities in total)
• Functional Keywords: cav1.3, channels, calcium ion-selective, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 429796.72

Authors

Gao, S.,Yao, X.,Yan, N. (deposition date: 2022-03-26, release date: 2022-05-11, Last modification date: 2022-10-12)

• Primary citation: Yao, X.,Gao, S.,Yan, N.; Structural basis for pore blockade of human voltage-gated calcium channel Ca v 1.3 by motion sickness drug cinnarizine.; Cell Res., 32:946-948, 2022; PubMed: 35477996; DOI: 10.1038/s41422-022-00663-5

Experimental method

ELECTRON MICROSCOPY (3.1 Å)