7U9O

SARS-CoV-2 spike trimer RBD in complex with Fab NE12

Summary for 7U9O

• Entry DOI: 10.2210/pdb7u9o/pdb
• EMDB information: 26402
• Descriptor: Spike glycoprotein, NE12 Fab heavy chain, NE12 Fab light chain, ... (4 entities in total)
• Functional Keywords: sars-cov-2, covid19, spike protein, antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 4
• Total formula weight: 330781.58

Authors

Tsybovsky, Y.,Kwong, P.D.,Farci, P. (deposition date: 2022-03-11, release date: 2022-11-23)

• Primary citation: Chen, Z.,Zhang, P.,Matsuoka, Y.,Tsybovsky, Y.,West, K.,Santos, C.,Boyd, L.F.,Nguyen, H.,Pomerenke, A.,Stephens, T.,Olia, A.S.,Zhang, B.,De Giorgi, V.,Holbrook, M.R.,Gross, R.,Postnikova, E.,Garza, N.L.,Johnson, R.F.,Margulies, D.H.,Kwong, P.D.,Alter, H.J.,Buchholz, U.J.,Lusso, P.,Farci, P.; Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.; Cell Rep, 41:111528-111528, 2022; PubMed: 36302375; DOI: 10.1016/j.celrep.2022.111528

Experimental method

ELECTRON MICROSCOPY (3.4 Å)