7TYF
Human Amylin1 Receptor in complex with Gs and rat amylin peptide
Summary for 7TYF
Entry DOI | 10.2210/pdb7tyf/pdb |
EMDB information | 26178 26179 26180 26184 26188 26190 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, CHOLESTEROL HEMISUCCINATE, (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, ... (13 entities in total) |
Functional Keywords | amylin receptor, gpcr, ramp, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 191919.95 |
Authors | Cao, J.,Belousoff, M.J.,Johnson, R.M.,Wootten, D.L.,Sexton, P.M. (deposition date: 2022-02-13, release date: 2022-03-23, Last modification date: 2024-10-09) |
Primary citation | Cao, J.,Belousoff, M.J.,Liang, Y.L.,Johnson, R.M.,Josephs, T.M.,Fletcher, M.M.,Christopoulos, A.,Hay, D.L.,Danev, R.,Wootten, D.,Sexton, P.M. A structural basis for amylin receptor phenotype. Science, 375:eabm9609-eabm9609, 2022 Cited by PubMed: 35324283DOI: 10.1126/science.abm9609 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.2 Å) |
Structure validation
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