7TJ9
Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN
Summary for 7TJ9
Entry DOI | 10.2210/pdb7tj9/pdb |
EMDB information | 25919 25920 |
Descriptor | Sodium channel protein type 7 subunit alpha, Sodium channel subunit beta-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | sodium channel, nav, ion channel, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 234368.40 |
Authors | Noland, C.L.,Kschonsak, M.,Ciferri, C.,Payandeh, J. (deposition date: 2022-01-14, release date: 2022-03-30, Last modification date: 2024-10-09) |
Primary citation | Noland, C.L.,Chua, H.C.,Kschonsak, M.,Heusser, S.A.,Braun, N.,Chang, T.,Tam, C.,Tang, J.,Arthur, C.P.,Ciferri, C.,Pless, S.A.,Payandeh, J. Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel. Nat Commun, 13:1416-1416, 2022 Cited by PubMed: 35301303DOI: 10.1038/s41467-022-28984-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
Download full validation report