7TA0
Human Ornithine Aminotransferase (hOAT) soaked with 5-aminovaleric acid
Summary for 7TA0
Entry DOI | 10.2210/pdb7ta0/pdb |
Descriptor | Ornithine aminotransferase, mitochondrial, 5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | human ornithine aminotransferase, hoat, oat, plp, 5-aminovaleric acid, soaking, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 147015.81 |
Authors | Butrin, A.,Liu, D. (deposition date: 2021-12-20, release date: 2022-05-04, Last modification date: 2023-10-18) |
Primary citation | Butrin, A.,Butrin, A.,Wawrzak, Z.,Moran, G.R.,Liu, D. Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298:101969-101969, 2022 Cited by PubMed: 35460691DOI: 10.1016/j.jbc.2022.101969 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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