7T2A
Crystal structure of HLA-DP4 in complex with Ply
Summary for 7T2A
Entry DOI | 10.2210/pdb7t2a/pdb |
Descriptor | HLA class II histocompatibility antigen, DP alpha 1 chain, HLA class II histocompatibility antigen, DP beta 1 chain, Pneumolysin-derived peptide, ... (4 entities in total) |
Functional Keywords | phla complex, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 90256.63 |
Authors | Ciacchi, L.,Farenc, C.,Petersen, J.,Reid, H.H.,Rossjohn, J. (deposition date: 2021-12-03, release date: 2022-12-28, Last modification date: 2023-10-25) |
Primary citation | Ciacchi, L.,van de Garde, M.D.B.,Ladell, K.,Farenc, C.,Poelen, M.C.M.,Miners, K.L.,Llerena, C.,Reid, H.H.,Petersen, J.,Price, D.A.,Rossjohn, J.,van Els, C.A.C.M. CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity. Immunity, 56:1082-1097.e6, 2023 Cited by PubMed: 37100059DOI: 10.1016/j.immuni.2023.03.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.04 Å) |
Structure validation
Download full validation report