7SJS

Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8

Summary for 7SJS

• Entry DOI: 10.2210/pdb7sjs/pdb
• Descriptor: CC40.8 Fab heavy chain, CC40.8 Fab light chain, stem helix peptide of Spike protein S2', ... (7 entities in total)
• Functional Keywords: sars-cov-2, antibody, spike, s2, stem helix, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 49177.54

Authors

Yuan, M.,Wilson, I.A. (deposition date: 2021-10-18, release date: 2022-01-12, Last modification date: 2023-10-18)

• Primary citation: Zhou, P.,Yuan, M.,Song, G.,Beutler, N.,Shaabani, N.,Huang, D.,He, W.T.,Zhu, X.,Callaghan, S.,Yong, P.,Anzanello, F.,Peng, L.,Ricketts, J.,Parren, M.,Garcia, E.,Rawlings, S.A.,Smith, D.M.,Nemazee, D.,Teijaro, J.R.,Rogers, T.F.,Wilson, I.A.,Burton, D.R.,Andrabi, R.; A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.; Sci Transl Med, 14:eabi9215-eabi9215, 2022; PubMed: 35133175; DOI: 10.1126/scitranslmed.abi9215

Experimental method

X-RAY DIFFRACTION (1.612 Å)