7SH9
Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI86
Summary for 7SH9
Entry DOI | 10.2210/pdb7sh9/pdb |
Descriptor | 3C-like proteinase nsp5, benzyl [(2S,3R)-1-({(2S)-1-[2-acetyl-2-(3-amino-3-oxopropyl)hydrazinyl]-3-cyclohexyl-1-oxopropan-2-yl}amino)-3-tert-butoxy-1-oxobutan-2-yl]carbamate (non-preferred name) (3 entities in total) |
Functional Keywords | main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 34463.27 |
Authors | Yang, K.S.,Liu, W.R. (deposition date: 2021-10-08, release date: 2023-04-12, Last modification date: 2023-11-15) |
Primary citation | Yang, K.S.,Sankaran, B.,Liu, W.R. Structure of the SARS-CoV-2 main protease in complex with inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report