7S9X
Crystal structure of CDK2 liganded with compound WN378
Summary for 7S9X
Entry DOI | 10.2210/pdb7s9x/pdb |
Descriptor | Cyclin-dependent kinase 2, 2-[(9H-carbazol-3-yl)amino]-5-(trifluoromethyl)benzoic acid (3 entities in total) |
Functional Keywords | allosteric inhibitor, drug development, kinase, cell cycle |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34346.81 |
Authors | Sun, L.,Schonbrunn, E. (deposition date: 2021-09-21, release date: 2022-10-05, Last modification date: 2023-10-18) |
Primary citation | Sun, L.,Schonbrunn, E. Development of selective allosteric inhibitors of cyclin-dependent kinase 2 (CDK2) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
Download full validation report