7S06
Cryo-EM structure of human GlcNAc-1-phosphotransferase A2B2 subcomplex
Summary for 7S06
Entry DOI | 10.2210/pdb7s06/pdb |
EMDB information | 24785 |
Descriptor | N-acetylglucosamine-1-phosphotransferase subunits alpha/beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | glcnac-1-phosphotransferase, lysosomal hydrolases, mannose 6-phosphate trafficking pathway, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 272599.85 |
Authors | |
Primary citation | Li, H.,Lee, W.S.,Feng, X.,Bai, L.,Jennings, B.C.,Liu, L.,Doray, B.,Canfield, W.M.,Kornfeld, S.,Li, H. Structure of the human GlcNAc-1-phosphotransferase alpha beta subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation. Nat.Struct.Mol.Biol., 29:348-356, 2022 Cited by PubMed: 35332324DOI: 10.1038/s41594-022-00748-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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