7RUD
DAHP synthase complex with trifluoropyruvate oxime
Summary for 7RUD
Entry DOI | 10.2210/pdb7rud/pdb |
Descriptor | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive, (2Z)-3,3,3-trifluoro-2-(hydroxyimino)propanoic acid (3 entities in total) |
Functional Keywords | dahp synthase, inhibitor, complex, lyase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 4 |
Total formula weight | 152937.36 |
Authors | Heimhalt, M.,Mukherjee, P.,Grainger, R.,Szabla, R.,Brown, C.,Turner, R.,Junop, M.S.,Berti, P.J. (deposition date: 2021-08-16, release date: 2021-11-17, Last modification date: 2023-10-18) |
Primary citation | Heimhalt, M.,Mukherjee, P.,Grainger, R.A.,Szabla, R.,Brown, C.,Turner, R.,Junop, M.S.,Berti, P.J. An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition. Acs Infect Dis., 7:3292-3302, 2021 Cited by PubMed: 34761906DOI: 10.1021/acsinfecdis.1c00462 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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