7R4R

The SARS-CoV-2 spike in complex with the 1.10 neutralizing nanobody

Summary for 7R4R

Entry DOI	10.2210/pdb7r4r/pdb
EMDB information	14315
Descriptor	Spike glycoprotein, Camel-derived nanobody 1.10, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	coronavirus, covid-19, sars-cov-2, spike, nanobodies, neutralization, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	4
Total formula weight	443084.46
Authors	Casasnovas, J.M.,Melero, R.,Arranz, R.,Fernandez, L.A. (deposition date: 2022-02-09, release date: 2022-06-08)
Primary citation	Casasnovas, J.M.,Margolles, Y.,Noriega, M.A.,Guzman, M.,Arranz, R.,Melero, R.,Casanova, M.,Corbera, J.A.,Jimenez-de-Oya, N.,Gastaminza, P.,Garaigorta, U.,Saiz, J.C.,Martin-Acebes, M.A.,Fernandez, L.A. Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron. Front Immunol, 13:863831-863831, 2022 Cited by PubMed: 35547740 DOI: 10.3389/fimmu.2022.863831 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation