7R40

Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment

Summary for 7R40

Entry DOI	10.2210/pdb7r40/pdb
EMDB information	14250
Descriptor	Spike glycoprotein, 87G7 light chain variable region, 87G7 heavy chain variable region, ... (5 entities in total)
Functional Keywords	coronavirus, spike, antibody, complex, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	9
Total formula weight	576609.36
Authors	Hurdiss, D.L. (deposition date: 2022-02-08, release date: 2022-04-20, Last modification date: 2023-12-13)
Primary citation	Du, W.,Hurdiss, D.L.,Drabek, D.,Mykytyn, A.Z.,Kaiser, F.K.,Gonzalez-Hernandez, M.,Munoz-Santos, D.,Lamers, M.M.,van Haperen, R.,Li, W.,Drulyte, I.,Wang, C.,Sola, I.,Armando, F.,Beythien, G.,Ciurkiewicz, M.,Baumgartner, W.,Guilfoyle, K.,Smits, T.,van der Lee, J.,van Kuppeveld, F.J.M.,van Amerongen, G.,Haagmans, B.L.,Enjuanes, L.,Osterhaus, A.D.M.E.,Grosveld, F.,Bosch, B.J. An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern. Sci Immunol, 7:eabp9312-eabp9312, 2022 Cited by PubMed: 35471062 DOI: 10.1126/sciimmunol.abp9312 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation