7QT0
Antibody FenAb136 - fentanyl complex
Summary for 7QT0
Entry DOI | 10.2210/pdb7qt0/pdb |
Descriptor | Antibody heavy chain, Antibody light chain, 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, ... (4 entities in total) |
Functional Keywords | antibody, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 12 |
Total formula weight | 291731.89 |
Authors | Zeelen, J.P.,Straaten van, M.,Stebbins, C.E. (deposition date: 2022-01-14, release date: 2023-05-24, Last modification date: 2024-02-07) |
Primary citation | Triller, G.,Vlachou, E.P.,Hashemi, H.,van Straaten, M.,Zeelen, J.P.,Kelemen, Y.,Baehr, C.,Marker, C.L.,Ruf, S.,Svirina, A.,Chandra, M.,Urban, K.,Gkeka, A.,Kruse, S.,Baumann, A.,Miller, A.K.,Bartel, M.,Pravetoni, M.,Stebbins, C.E.,Papavasiliou, F.N.,Verdi, J.P. A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42:112049-112049, 2023 Cited by PubMed: 36719797DOI: 10.1016/j.celrep.2023.112049 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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