7PUI
Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 2-pyridineboronic acid
Summary for 7PUI
Entry DOI | 10.2210/pdb7pui/pdb |
Descriptor | Cholinephosphate cytidylyltransferase, pyridin-2-ylboronic acid (3 entities in total) |
Functional Keywords | plasmodium falciparum cct inhibitors fragments, transferase |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 1 |
Total formula weight | 20933.04 |
Authors | Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-09-30, release date: 2022-10-05, Last modification date: 2024-01-31) |
Primary citation | Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
Download full validation report