7PQT
Apo human Kv3.1 cryo-EM structure
Summary for 7PQT
Entry DOI | 10.2210/pdb7pqt/pdb |
EMDB information | 13604 |
Descriptor | Potassium voltage-gated channel subfamily C member 1, POTASSIUM ION (3 entities in total) |
Functional Keywords | potassium ion channel, voltage gated, drug target, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 235689.11 |
Authors | Botte, M.,Huber, S.,Bucher, D.,Klint, J.K.,Rodriguez, D.,Tagmose, L.,Chami, M.,Cheng, R.,Hennig, M.,Abdul Rhaman, W. (deposition date: 2021-09-20, release date: 2022-08-17, Last modification date: 2024-07-17) |
Primary citation | Botte, M.,Huber, S.,Bucher, D.,Klint, J.K.,Rodriguez, D.,Tagmose, L.,Chami, M.,Cheng, R.,Hennig, M.,Abdul Rahman, W. Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1:pgac083-pgac083, 2022 Cited by PubMed: 36741467DOI: 10.1093/pnasnexus/pgac083 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.65 Å) |
Structure validation
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