7PG8
NaV_Ae1/Sp1CTD_pore-ANT05 complex
Summary for 7PG8
Entry DOI | 10.2210/pdb7pg8/pdb |
Descriptor | ANT05 H12 fab fragment, light chain, ANT05 H12 fab fragment, heavy chain, Ion transport protein,Voltage-gated sodium channel (3 entities in total) |
Functional Keywords | ion channel membrane protein transport protein antibody complex, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 24 |
Total formula weight | 515691.68 |
Authors | Lolicato, M.,Arrigoni, C. (deposition date: 2021-08-13, release date: 2022-06-08, Last modification date: 2024-01-31) |
Primary citation | Arrigoni, C.,Lolicato, M.,Shaya, D.,Rohaim, A.,Findeisen, F.,Fong, L.K.,Colleran, C.M.,Dominik, P.,Kim, S.S.,Schuermann, J.P.,DeGrado, W.F.,Grabe, M.,Kossiakoff, A.A.,Minor Jr., D.L. Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29:537-548, 2022 Cited by PubMed: 35655098DOI: 10.1038/s41594-022-00775-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.5 Å) |
Structure validation
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