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7P40

P5C3 is a potent fab neutralizer

Replaces:  7NY5
Summary for 7P40
Entry DOI10.2210/pdb7p40/pdb
EMDB information13190
DescriptorSpike glycoprotein, Variable Light Chain P5C3 (VL), Variable Heavy Chain P5C3 (VH) (3 entities in total)
Functional Keywordsspike, antibody, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
More
Total number of polymer chains9
Total formula weight564935.60
Authors
perez, L. (deposition date: 2021-07-09, release date: 2021-10-13, Last modification date: 2023-04-12)
Primary citationFenwick, C.,Turelli, P.,Perez, L.,Pellaton, C.,Esteves-Leuenberger, L.,Farina, A.,Campos, J.,Lana, E.,Fiscalini, F.,Raclot, C.,Pojer, F.,Lau, K.,Demurtas, D.,Descatoire, M.,Joo, V.S.,Foglierini, M.,Noto, A.,Abdelnabi, R.,Foo, C.S.,Vangeel, L.,Neyts, J.,Du, W.,Bosch, B.J.,Veldman, G.,Leyssen, P.,Thiel, V.,LeGrand, R.,Levy, Y.,Trono, D.,Pantaleo, G.
A highly potent antibody effective against SARS-CoV-2 variants of concern.
Cell Rep, 37:109814-109814, 2021
Cited by
PubMed: 34599871
DOI: 10.1016/j.celrep.2021.109814
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.5 Å)
Structure validation

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