7P1R

Structure of Trichophyton Rubrum KDNase in complex with 2,3-difluoro-KDN

Summary for 7P1R

Entry DOI	10.2210/pdb7p1r/pdb
Descriptor	Extracellular sialidase/neuraminidase, PHOSPHATE ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	carbohydrate metabolism, enzyme structure, protein structure, kdn, kdnase, sialic acid, sialidase, trichophyton rubrum, carbohydrate
Biological source	Trichophyton rubrum (Athlete's foot fungus, Epidermophyton rubrum)
Total number of polymer chains	4
Total formula weight	170856.34
Authors	Gloster, T.M.,McMahon, S.A. (deposition date: 2021-07-02, release date: 2021-10-20, Last modification date: 2024-01-31)
Primary citation	Nejatie, A.,Steves, E.,Gauthier, N.,Baker, J.,Nesbitt, J.,McMahon, S.A.,Oehler, V.,Thornton, N.J.,Noyovitz, B.,Khazaei, K.,Byers, B.W.,Zandberg, W.F.,Gloster, T.M.,Moore, M.M.,Bennet, A.J. Kinetic and Structural Characterization of Sialidases (Kdnases) from Ascomycete Fungal Pathogens. Acs Chem.Biol., 16:2632-2640, 2021 Cited by PubMed: 34724608 DOI: 10.1021/acschembio.1c00666 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation