7OYJ
Crystal structure of hTEAD2 in complex with fragment at the interface 2
Summary for 7OYJ
Entry DOI | 10.2210/pdb7oyj/pdb |
Descriptor | Transcriptional enhancer factor TEF-4, PALMITIC ACID, 3-(1~{H}-pyrazol-5-yl)aniline, ... (4 entities in total) |
Functional Keywords | tead, fragment, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 55650.23 |
Authors | Guichou, J.F.,Gelin, M.,Allemand, F. (deposition date: 2021-06-24, release date: 2022-05-25, Last modification date: 2024-01-31) |
Primary citation | Liberelle, M.,Toulotte, F.,Renault, N.,Gelin, M.,Allemand, F.,Melnyk, P.,Guichou, J.F.,Cotelle, P. Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs. J.Med.Chem., 65:5926-5940, 2022 Cited by PubMed: 35389210DOI: 10.1021/acs.jmedchem.2c00075 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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