7OJM
CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) CATALYTICALLY INACTIVE H251A VARIANT COMPLEXED WITH 2-METHYL-QUINOLIN-4(1H)-ONE UNDER NORMOXIC CONDITIONS
This is a non-PDB format compatible entry.
Summary for 7OJM
Entry DOI | 10.2210/pdb7ojm/pdb |
Descriptor | 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-methyl-quinolin-4(1H)-one, POTASSIUM ION, ... (7 entities in total) |
Functional Keywords | alpha-beta hydrolase complex, oxidoreductase, dioxygenase, cofactor-devoid |
Biological source | Paenarthrobacter nitroguajacolicus (Arthrobacter nitroguajacolicus) |
Total number of polymer chains | 2 |
Total formula weight | 67779.93 |
Authors | Bui, S.,Steiner, R.A. (deposition date: 2021-05-16, release date: 2022-06-01, Last modification date: 2024-01-31) |
Primary citation | Bui, S.,Gil-Guerrero, S.,van der Linden, P.,Carpentier, P.,Ceccarelli, M.,Jambrina, P.G.,Steiner, R.A. Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold. Chem Sci, 14:10547-10560, 2023 Cited by PubMed: 37799987DOI: 10.1039/d3sc03044j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.001 Å) |
Structure validation
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