7OH1
Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1
Summary for 7OH1
| Entry DOI | 10.2210/pdb7oh1/pdb |
| EMDB information | 12890 12891 |
| Descriptor | Tetanus toxin, FAB TT110 (3 entities in total) |
| Functional Keywords | tetanus, tetanus neurotoxin, humabs, monoclonal antibody, tetanus prophylaxis, spastic paralysis, tetanus immunoglobulin, tig, toxin |
| Biological source | Clostridium tetani More |
| Total number of polymer chains | 3 |
| Total formula weight | 147246.13 |
| Authors | Grinzato, A.,Kandiah, E.,Zanotti, G. (deposition date: 2021-05-07, release date: 2021-10-27, Last modification date: 2021-11-24) |
| Primary citation | Pirazzini, M.,Grinzato, A.,Corti, D.,Barbieri, S.,Leka, O.,Vallese, F.,Tonellato, M.,Silacci-Fregni, C.,Piccoli, L.,Kandiah, E.,Schiavo, G.,Zanotti, G.,Lanzavecchia, A.,Montecucco, C. Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice. J.Clin.Invest., 131:-, 2021 Cited by PubMed: 34618682DOI: 10.1172/JCI151676 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (8 Å) |
Structure validation
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