7NY8
Affimer K69 - KRAS protein complex
Summary for 7NY8
Entry DOI | 10.2210/pdb7ny8/pdb |
Related | 6YR8 6YXW |
Descriptor | GTPase KRas, Affimer K69, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | protein complex, affimer, kras, inhibitor, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 64785.17 |
Authors | Turner, A.L.,Trinh, C.H.,Haza, K.Z.,Rao, A.,Martin, H.L.,Tiede, C.,Edwards, T.A.,McPherson, M.J.,Tomlinson, D.C. (deposition date: 2021-03-21, release date: 2021-07-07, Last modification date: 2024-01-31) |
Primary citation | Haza, K.Z.,Martin, H.L.,Rao, A.,Turner, A.L.,Saunders, S.E.,Petersen, B.,Tiede, C.,Tipping, K.,Tang, A.A.,Ajayi, M.,Taylor, T.,Harvey, M.,Fishwick, K.M.,Adams, T.L.,Gaule, T.G.,Trinh, C.H.,Johnson, M.,Breeze, A.L.,Edwards, T.A.,McPherson, M.J.,Tomlinson, D.C. RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site. Nat Commun, 12:4045-4045, 2021 Cited by PubMed: 34193876DOI: 10.1038/s41467-021-24316-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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