7NL5
Structure of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol trisaccharide inhibitor
Summary for 7NL5
Entry DOI | 10.2210/pdb7nl5/pdb |
Descriptor | Alpha-1,6-mannanase, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, (1R,6S)-5beta-(Hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2beta,3beta,4alpha-triol, ... (5 entities in total) |
Functional Keywords | mannanase, cyclophellitol, epoxide, hydrolase |
Biological source | Bacillus circulans |
Total number of polymer chains | 1 |
Total formula weight | 41627.51 |
Authors | Schroeder, S.,Offen, W.A.,Males, A.,Jin, Y.,De Boer, C.,Enotarpi, J.,Marino, L.,van der Marel, G.A.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2021-02-22, release date: 2021-04-28, Last modification date: 2024-10-16) |
Primary citation | Schroder, S.P.,Offen, W.A.,Males, A.,Jin, Y.,de Boer, C.,Enotarpi, J.,Marino, L.,van der Marel, G.A.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Davies, G.J. Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases. Chemistry, 27:9519-9523, 2021 Cited by PubMed: 33878235DOI: 10.1002/chem.202101255 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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