7NC6
Glutathione-S-transferase GliG in complex with cyclo[L-Phe-L-Ser]-bis-glutathione-adduct
Summary for 7NC6
Entry DOI | 10.2210/pdb7nc6/pdb |
Related | 7NC3 7NC5 |
Descriptor | Glutathione S-transferase GliG, (2~{S})-2-azanyl-5-[[(2~{R})-3-[(2~{R},5~{R})-5-(hydroxymethyl)-3,6-bis(oxidanylidene)-2-(phenylmethyl)-5-sulfanyl-piperazin-2-yl]sulfanyl-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-propan-2-yl]amino]-5-oxidanylidene-pentanoic acid, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | aspergillus fumigatus, mycotoxin, glutathione-s-transferase, carbon-sulphur-bond, epidithiodioxopiperazine, biosynthetic protein |
Biological source | Aspergillus fumigatus A1163 |
Total number of polymer chains | 6 |
Total formula weight | 177453.08 |
Authors | Groll, M.,Huber, E.M. (deposition date: 2021-01-28, release date: 2021-05-12, Last modification date: 2024-01-31) |
Primary citation | Scherlach, K.,Kuttenlochner, W.,Scharf, D.H.,Brakhage, A.A.,Hertweck, C.,Groll, M.,Huber, E.M. Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60:14188-14194, 2021 Cited by PubMed: 33909314DOI: 10.1002/anie.202104372 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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