7MQ6

Tetragonal Maltose Binding Protein in the presence of gold

Summary for 7MQ6

Entry DOI	10.2210/pdb7mq6/pdb
Related PRD ID	PRD_900018
Descriptor	Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, GOLD ION, ... (6 entities in total)
Functional Keywords	maltose binding protein, gold, sugar binding protein
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	42291.73
Authors	Thaker, A.,Sirajudeen, L.,Simmons, C.R.,Nannenga, B.L. (deposition date: 2021-05-05, release date: 2021-09-08, Last modification date: 2023-10-18)
Primary citation	Thaker, A.,Sirajudeen, L.,Simmons, C.R.,Nannenga, B.L. Structure-guided identification of a peptide for bio-enabled gold nanoparticle synthesis. Biotechnol.Bioeng., 118:4867-4873, 2021 Cited by PubMed Abstract: In this study, we show that maltose-binding protein (MBP) is capable of facilitating stable gold nanoparticle synthesis, and a structure of MBP in the presence of gold ions was determined by X-ray crystallography. Using this high-resolution structure of gold ion bound MBP, a peptide (AT1) was selected and synthesized and was shown to also aid in the synthesis of stable gold nanoparticles under similar experimental conditions to those used for protein facilitated synthesis. This structure-based approach represents a new potential method for the selection of peptides capable of facilitating stable nanoparticle synthesis. PubMed: 34436761 DOI: 10.1002/bit.27927 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.372 Å)

Structure validation