7MO9
Cryo-EM map of the c-MET II/HGF I/HGF II (K4 and SPH) sub-complex
Summary for 7MO9
Entry DOI | 10.2210/pdb7mo9/pdb |
EMDB information | 23919 23920 23921 |
Descriptor | Hepatocyte growth factor, Hepatocyte growth factor receptor, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | c-met, hgf, receptor tyrosine kinase, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 323970.71 |
Authors | Uchikawa, E.,Chen, Z.M.,Xiao, G.Y.,Zhang, X.W.,Bai, X.C. (deposition date: 2021-05-01, release date: 2021-06-09, Last modification date: 2021-07-28) |
Primary citation | Uchikawa, E.,Chen, Z.,Xiao, G.Y.,Zhang, X.,Bai, X.C. Structural basis of the activation of c-MET receptor. Nat Commun, 12:4074-4074, 2021 Cited by PubMed: 34210960DOI: 10.1038/s41467-021-24367-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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