7MJI
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8 (focused refinement of RBD and VH ab8)
Summary for 7MJI
Entry DOI | 10.2210/pdb7mji/pdb |
EMDB information | 23874 |
Descriptor | Spike glycoprotein, VH ab8, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | sars-cov-2, glycoprotein, fusion protein, viral protein, vh ab8, neutralizing antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 2 |
Total formula weight | 158671.17 |
Authors | Zhu, X.,Mannar, D.,Srivastava, S.S.,Berezuk, A.M.,Demers, J.P.,Saville, J.W.,Leopold, K.,Li, W.,Dimitrov, D.S.,Tuttle, K.S.,Zhou, S.,Chittori, S.,Subramaniam, S. (deposition date: 2021-04-20, release date: 2021-05-12) |
Primary citation | Zhu, X.,Mannar, D.,Srivastava, S.S.,Berezuk, A.M.,Demers, J.P.,Saville, J.W.,Leopold, K.,Li, W.,Dimitrov, D.S.,Tuttle, K.S.,Zhou, S.,Chittori, S.,Subramaniam, S. Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies. Plos Biol., 19:e3001237-e3001237, 2021 Cited by PubMed: 33914735DOI: 10.1371/journal.pbio.3001237 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.81 Å) |
Structure validation
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