7M95
Bovine sigma-2 receptor bound to Z1241145220
Summary for 7M95
Entry DOI | 10.2210/pdb7m95/pdb |
Descriptor | Sigma intracellular receptor 2, 3-[1-(3-phenylpropyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine, CHOLESTEROL, ... (5 entities in total) |
Functional Keywords | receptor, sterol, dimer, membrane protein |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 2 |
Total formula weight | 44690.16 |
Authors | Alon, A.,Kruse, A.C. (deposition date: 2021-03-30, release date: 2021-12-15, Last modification date: 2023-10-18) |
Primary citation | Alon, A.,Lyu, J.,Braz, J.M.,Tummino, T.A.,Craik, V.,O'Meara, M.J.,Webb, C.M.,Radchenko, D.S.,Moroz, Y.S.,Huang, X.P.,Liu, Y.,Roth, B.L.,Irwin, J.J.,Basbaum, A.I.,Shoichet, B.K.,Kruse, A.C. Structures of the sigma 2 receptor enable docking for bioactive ligand discovery. Nature, 600:759-764, 2021 Cited by PubMed: 34880501DOI: 10.1038/s41586-021-04175-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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