7LBR
SARS-CoV-2 papain-like protease (PLpro) bound to inhibitor XR8-89
Summary for 7LBR
Entry DOI | 10.2210/pdb7lbr/pdb |
Descriptor | Non-structural protein 3, ZINC ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | papain-like protease, coronavirus inhibitor, sars-cov-2, viral protein, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 2 |
Total formula weight | 73225.79 |
Authors | Ratia, K.M.,Xiong, R.,Thatcher, G.R. (deposition date: 2021-01-08, release date: 2021-02-24, Last modification date: 2023-10-18) |
Primary citation | Shen, Z.,Ratia, K.,Cooper, L.,Kong, D.,Lee, H.,Kwon, Y.,Li, Y.,Alqarni, S.,Huang, F.,Dubrovskyi, O.,Rong, L.,Thatcher, G.R.,Xiong, R. Potent, Novel SARS-CoV-2 PLpro Inhibitors Block Viral Replication in Monkey and Human Cell Cultures. Biorxiv, 2021 Cited by PubMed: 33594371DOI: 10.1101/2021.02.13.431008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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