7L2V
cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state b
Summary for 7L2V
Entry DOI | 10.2210/pdb7l2v/pdb |
EMDB information | 23142 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, resiniferatoxin, 6-deoxy-6-(methylamino)-D-galactitol, ... (4 entities in total) |
Functional Keywords | trp channel, cryo-em, nanodisc, large cation, vanilloid agonist, transport protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 294798.44 |
Authors | Zhang, K.,Julius, D.,Cheng, Y. (deposition date: 2020-12-17, release date: 2021-09-22, Last modification date: 2024-05-29) |
Primary citation | Zhang, K.,Julius, D.,Cheng, Y. Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184:5138-, 2021 Cited by PubMed: 34496225DOI: 10.1016/j.cell.2021.08.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.64 Å) |
Structure validation
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