7KZL

Cyclopentane peptide nucleic acid in complex with DNA

Summary for 7KZL

• Entry DOI: 10.2210/pdb7kzl/pdb
• Descriptor: DNA (5'-D(*TP*AP*TP*CP*AP*CP*AP*TP*C)-3'), XDJ-XDD-XDY-XDJ-XDY-XDJ-XDD-XDY-XDD-XDV, IODIDE ION, ... (7 entities in total)
• Functional Keywords: peptide nucleic acid, pna, peptide nucleic acid-dna complex, peptide nucleic acid/dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 6373.46

Authors

Botos, I.,Appella, D.H. (deposition date: 2020-12-10, release date: 2020-12-23, Last modification date: 2024-04-03)

• Primary citation: Zheng, H.,Botos, I.,Clausse, V.,Nikolayevskiy, H.,Rastede, E.E.,Fouz, M.F.,Mazur, S.J.,Appella, D.H.; Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA.; Nucleic Acids Res., 49:713-725, 2021; PubMed: 33406227; DOI: 10.1093/nar/gkaa1249

Experimental method

X-RAY DIFFRACTION (1.3 Å)