7KYF

Botulism Neurooxin Light Chain A app form

Summary for 7KYF

Entry DOI	10.2210/pdb7kyf/pdb
Descriptor	Bont/A1, ZINC ION, N-[(3,5-dichlorophenyl)sulfonyl]-L-isoleucyl-N-hydroxy-L-norvalinamide, ... (4 entities in total)
Functional Keywords	bont, botulinum neurotoxin nva-ila dipetpide bound, toxin
Biological source	Clostridium botulinum
Total number of polymer chains	1
Total formula weight	48296.82
Authors	Ortega, M.E.,Salzameda, N.T. (deposition date: 2020-12-07, release date: 2021-04-14, Last modification date: 2023-10-18)
Primary citation	Amezcua, M.,Cruz, R.S.,Ku, A.,Moran, W.,Ortega, M.E.,Salzameda, N.T. Discovery of Dipeptides as Potent Botulinum Neurotoxin A Light-Chain Inhibitors. Acs Med.Chem.Lett., 12:295-301, 2021 Cited by PubMed: 33603978 DOI: 10.1021/acsmedchemlett.0c00674 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation