7KOZ
CD1a-36:2 SM binary complex
Summary for 7KOZ
Entry DOI | 10.2210/pdb7koz/pdb |
Descriptor | T-cell surface glycoprotein CD1a, Beta-2-microglobulin, (4S,7S,17Z)-4-hydroxy-7-[(1S,2E)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-4,9-dioxo-3,5-dioxa-8-aza-4lambda~5~-phosphahexacos-17-en-1-aminium, ... (6 entities in total) |
Functional Keywords | cd1, antigen presentation, lipid, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 46093.96 |
Authors | Wegrecki, M.,Le Nours, J.,Rossjohn, J. (deposition date: 2020-11-10, release date: 2021-05-05, Last modification date: 2023-10-18) |
Primary citation | Cotton, R.N.,Wegrecki, M.,Cheng, T.Y.,Chen, Y.L.,Veerapen, N.,Le Nours, J.,Orgill, D.P.,Pomahac, B.,Talbot, S.G.,Willis, R.,Altman, J.D.,de Jong, A.,Van Rhijn, I.,Clark, R.A.,Besra, G.S.,Ogg, G.,Rossjohn, J.,Moody, D.B. CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218:-, 2021 Cited by PubMed: 33961028DOI: 10.1084/jem.20202699 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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