7KI0
Semaglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs protein
Summary for 7KI0
Entry DOI | 10.2210/pdb7ki0/pdb |
EMDB information | 22882 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total) |
Functional Keywords | glucagon-like peptide-1 (glp-1) receptor semaglutide cryoem, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 163832.55 |
Authors | Zhang, X.,Belousoff, M.J.,Danev, R.,Sexton, P.M.,Wootten, D. (deposition date: 2020-10-22, release date: 2021-08-04) |
Primary citation | Zhang, X.,Belousoff, M.J.,Liang, Y.L.,Danev, R.,Sexton, P.M.,Wootten, D. Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes. Cell Rep, 36:109374-109374, 2021 Cited by PubMed: 34260945DOI: 10.1016/j.celrep.2021.109374 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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