7K9Z

Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52

Summary for 7K9Z

• Entry DOI: 10.2210/pdb7k9z/pdb
• Descriptor: 52 Fab Heavy Chain, 52 Fab Light Chain, 298 Fab Light Chain, ... (6 entities in total)
• Functional Keywords: sars-cov-2, receptor binding domain, neutralizing antibodies, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 120012.92

Authors

Newton, J.C.,Kucharska, I.,Rujas, E.,Cui, H.,Julien, J.P. (deposition date: 2020-09-29, release date: 2020-10-28, Last modification date: 2023-10-18)

• Primary citation: Rujas, E.,Kucharska, I.,Tan, Y.Z.,Benlekbir, S.,Cui, H.,Zhao, T.,Wasney, G.A.,Budylowski, P.,Guvenc, F.,Newton, J.C.,Sicard, T.,Semesi, A.,Muthuraman, K.,Nouanesengsy, A.,Aschner, C.B.,Prieto, K.,Bueler, S.A.,Youssef, S.,Liao-Chan, S.,Glanville, J.,Christie-Holmes, N.,Mubareka, S.,Gray-Owen, S.D.,Rubinstein, J.L.,Treanor, B.,Julien, J.P.; Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.; Nat Commun, 12:3661-3661, 2021; PubMed: 34135340; DOI: 10.1038/s41467-021-23825-2

Experimental method

X-RAY DIFFRACTION (2.95 Å)