7K8M
Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102
Summary for 7K8M
Entry DOI | 10.2210/pdb7k8m/pdb |
Descriptor | C102 Fab Heavy Chain, C102 Fab Light Chain, Spike glycoprotein, ... (4 entities in total) |
Functional Keywords | human neutralizing antibody, sars-cov-2, receptor binding domain, covid-19, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 69414.22 |
Authors | Jette, C.A.,Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-09-27, release date: 2020-10-21, Last modification date: 2023-10-18) |
Primary citation | Barnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J. SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588:682-687, 2020 Cited by PubMed: 33045718DOI: 10.1038/s41586-020-2852-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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