7I83

Crystal Structure of 33 bound to CK2a

This is a non-PDB format compatible entry.

Summary for 7I83

• Entry DOI: 10.2210/pdb7i83/pdb
• Group deposition: the group title you wish to show (G_1002301)
• Descriptor: Casein kinase II subunit alpha, ACETATE ION, N~1~-[(2-chloro[1,1'-biphenyl]-4-yl)methyl]-N~4~-(2-{[(8P)-8-(1H-tetrazol-5-yl)benzo[c][2,6]naphthyridin-5-yl]amino}ethyl)butane-1,4-diamine, ... (4 entities in total)
• Functional Keywords: fragment based drug discovery, kinase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39727.59

Authors

Brear, P.,Glossop, P.,Pandey, S.,Hyvonen, M.,Spring, D.,Butt, R.,Cawkill, D. (deposition date: 2025-03-12, release date: 2026-01-14)

• Primary citation: Glossop, P.,Brear, P.,Pandey, S.,Hyvonen, M.,Spring, D.,Butt, R.,Cawkill, D.; Anti-tumor Efficacy of CK2α inhibition in Wnt-Driven Colorectal Cancer; To be published,

Experimental method

X-RAY DIFFRACTION (1.51 Å)